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Schultz, M.B., Kane, A.E., Mitchell, S.J. et al. Age and life expectancy clocks based on machine learning analysis of mouse frailty. Nat Commun 11, 4618 (2020). https://doi.org/10.1038/s41467-020-18446-0  

PRESIDENT AND FELLOWS OF HARVARD COLLEGE​

The faculty at the Blavatnik Institute at Harvard Medical School are focused on solving human health challenges through fundamental and translational biomedical research.

VoLo Foundation’s grant to Harvard University for Harvard Medical School is a 3-year partnership to establish the current-use VoLo Research Fund on Aging specifically in support of the work of David A. Sinclair, PhD., Professor of Genetics in the Blavatnik Institute at Harvard Medical School and co-director of the Paul F. Glenn Center for Biology of Aging Research. The primary purpose of the grant is to fund studies focused on understanding how to accurately measure the pace of aging in humans and what aging clocks represent in terms of future health through animal model studies.

Click here to read an article spotlight on VoLo Foundation’s partnership with Harvard Medical School on page 10. 

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Sejad Al-Tahan, Lan Weiss, Howard Yu, Sha Tang, Mario Saporta, Anna Vihola, Tahseen Mozaffar, Bjarne Udd, Virginia Kimonis. New family with HSPB8-associated autosomal dominant rimmed vacuolar myopathy.  Neurol Genet Aug 2019, 5 (4) e349; DOI: 10.1212/NXG.0000000000000349 

UNIVERSITY OF CALIFORNIA – IRVINE​

The Kimonis Laboratory is a molecular genetics lab within the Division of Genetics & Genomic Medicine at UC Irvine School of Medicine Department of PediatricsThey are scientists and doctors studying genetic causes of muscle disease and the natural history of Prader-Willi Syndrome. Dr. Virginia E. Kimonis is particularly interested in inherited muscle disorders that occur in combination with diseases of bone and/or frontotemporal dementia

VoLo’s grant to UCI supports their research at this lab to find a cure for people suffering from inclusion body myopathy

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  1. Perez C, Prajapati K, Burke B, et alNKG2D signaling certifies effector CD8 T cells for memory formation. Journal for ImmunoTherapy of Cancer 2019;7:48. DOI: 10.1186/s40425-019-0531-2 
  2. Brianna Burke, Catherine Eden, Cynthia Perez, Alex Belshoff, Spencer Hart, Lourdes Plaza-Rojas, Michael Delos Reyes, Kushal Prajapati, Christina Voelkel-Johnson, Elizabeth Henry, Gopal Gupta and José Guevara-Patiño. Inhibition of Histone Deacetylase (HDAC) Enhances Checkpoint Blockade Efficacy by Rendering Bladder Cancer Cells Visible for T Cell-Mediated Destruction. Front. Oncol., 15 May 2020 | https://doi.org/10.3389/fonc.2020.00699  

MOFFITT CANCER CENTER FOUNDATION​

The Moffit Cancer Center is focused on two main areas in the development of curative immunologically-based approaches against cancer: understanding how ani-tumor responses can be generated, maintained and rescued in cancer patients; and the development of strategies that predict clinical responses in patients receiving checkpoint blockade therapy.

VoLo Foundation’s grant aids the ongoing work of Dr. Jose Guevara- Patiño, MD, Ph.D., and his team, as they strive forward in their bladder and kidney research and using the immune system to battle cancer.

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SCRIPPS RESEARCH

Scripps Research is a scientific institute where ambitious teams across 200 laboratories collaborate across disciplines to uncover new biological processes, create more efficient chemical reactions, and expand knowledge in fundamental life science.

VoLo Foundation Health provides support for The Prospective Electronic Polygenic Risk Study (PEPRS) under the leadership of Prof. Ali Torkamani, Director of Drug Discovery at the Scripps Translational Science Institute in La Jolla. This study investigates the role of polygenic risk scores (PRS) in preventive health.

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university of california san fransico

The UC San Francisco Department of Psychiatry and Behavioral Sciences is among the nation’s foremost resources in the fields of child, adolescent, adult, and geriatric mental health. It is one of the largest departments in the UCSF School of Medicine and the UCSF Weill Institute for Neurosciences focuses on research (basic, translational, clinical), teaching, patient care, and public service.

The Volo Foundation Health team provides support for the BOOST study under the leadership of Prof. and Vice Chair Elissa Epel and Prof. Aric Prather at the UCSF Department of Psychiatry and Behavioral Sciences. The study investigates the effects of immune aging, stress, and sleeping on the long-term effectiveness COVID-19 vaccine responses

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